Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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To assess the value of background continuity and amplitude fluctuations of the EEG for the prediction of outcome of comatose patients after cardiac arrest. ⋯ The presented features provide an objective, rapid, and reliable tool to assist in EEG interpretation in the Intensive Care Unit.
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Randomized Controlled Trial Multicenter Study Observational Study
Time to epileptiform activity and EEG background recovery are independent predictors after cardiac arrest.
Investigate the temporal development of EEG and prognosis. ⋯ Patients with early background recovery combined with late appearance of epileptiform activity may have a good outcome.
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Rapid eye movement (REM) sleep behavior disorder (RBD) involves REM sleep without atonia in conjunction with a recurrent nocturnal dream enactment behavior, with vocalizations such as shouting and screaming, and motor behaviors such as punching and kicking. Secondary RBD is well described in association with neurological disorders including Parkinson's disease (PD), multiple system atrophy (MSA), and other conditions involving brainstem structures such as tumors. However, RBD alone is now considered to be a potential harbinger of later development of neurodegenerative disorders, in particular PD, MSA, dementia with Lewy bodies (DLB), and pure autonomic failure. ⋯ A critical need is to improve our ability to counsel patients, particularly with regard to prognosis. The ability to identify who, of those with RBD, is at high risk for later neurodegenerative disorders will be paramount, and would in addition advance our understanding of the prodromal stages of the alpha-synucleinopathies. Moreover, recognition of at-risk individuals for neurodegenerative disorders may ultimately provide a platform for the testing of possible neuroprotective agents for these neurodegenerative disorders.