Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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The aim of this study was to assess the effect of central sensitization, induced by high frequency electrical stimulation of the skin (HFS), on pinprick-evoked brain potentials (PEPs) using robot-controlled mechanical pinprick stimulation and a stimulus evaluation task. ⋯ This is the first study that shows a significant increase of both PEP peaks, and therefore, it provides a preferred setup for assessing the function of mechanical nociceptive pathways in the context of central sensitization.
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Editorial Comment
Isolated REM sleep without atonia: The unsung hero of polysomnography.