International journal of burns and trauma
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Stem cell therapy application is at the vanguard of regenerative medicine across all medical disciplines. Stem cells are of special interest in burn wounds, as they have multiple potential indications for application; including - accelerating wound healing, improving skin regeneration to incorporate skin appendages, reducing fibrosis and improving scarring. ⋯ Stem cells accelerate burn wound healing by inducing neo-angiogenesis, collagen deposition and granulation tissue formation. They modulate the inflammatory response and reduce the risk of infection. They can regenerate skin appendages and halt he zone of stasis in acute burn injury. However with these pre-clinical animal model studies we must be cautious with our interpretation of this novel therapy.
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Burn is one of the injuries causing enormous pain among the patients, and the treatment procedure poses great anxiety. This study was designed to determine the effect of early change of skin graft on the pain and anxiety of the patients.
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Burns remained a major health problem in most developing countries which have increased the mortality and morbidity among the people. This study aimed to describe the epidemiology and outcomes of burn among females at reproductive age and investigate the factors that associated with mortality during the study period in in Baghdad/Iraq. ⋯ The patients at age 26-45 years have equal hazard ratio of death (HR=1) at all the times of follow-upping. There is not statistically significant have been found at the (p. value =0.486), the 95% CI for the HR includes the null value of 1. As well the causes of burn, the patients with fire cause have a higher hazard of death HR=1.1 with the (p. value =0.012). Half of cases were single. A significant relationship has been found between the marital status and the age groups of the p. value 0.000. Also, a significant result of the intent status with causes of burn at the p. value 0.000.