The American journal of otology
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Randomized Controlled Trial Clinical Trial
Efficacy of ondansetron for prevention of postoperative nausea and vomiting after outpatient ear surgery under local anesthesia.
To assess the efficacy and safety of intravenous ondansetron (4 mg) for the prevention of nausea and vomiting after middle ear surgery under local anesthesia. ⋯ Single-dose ondansetron (4 mg) given intravenously preoperatively significantly reduces postoperative vomiting in patients after tympanoplasty under local anesthesia and causes no adverse effects.
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To measure the middle ear (ME) volume displaced when the pars tensa (PT) retracts during conditions of atelectasis (AT). ⋯ Retraction of the PT may counteract an important potential negative ME pressure (up to several hundred millimeters of water) depending on the degree of retraction and the extent of mastoid pneumatization.