Giornale italiano di medicina del lavoro ed ergonomia
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G Ital Med Lav Ergon · Apr 2012
Novel tools for blood inflammatory markers detection in monitoring air pollution-induced cardio-respiratory symptoms.
There is strong epidemiological evidence that air pollution exposure (short- and long-term, i.e. < 24 hr to 3 weeks, and year/s) is related to exacerbation of cardiovascular and respiratory diseases. Data from toxicological and basic science/molecular studies, controlled animal and human exposures and human panel studies have demonstrated several mechanisms by which particle exposure may both trigger acute events as well as prompt the chronic development of cardiovascular diseases. These pollutant-mediated biological mechanisms are supporting the potential use of haematic (inflammation/coagulation/oxidative stress) markers of effects in cardio-respiratory diseases. Various examples from in vitro, in vivo and epidemiological investigations are reported, together with some novel technologies that should provide with new tools for research in these diseases and improve the knowledge about any linkage of local and systemic inflammation and clinical features of these diseases (in particular COPD), including lung function, exacerbations, disease progression, and mortality.
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G Ital Med Lav Ergon · Apr 2012
Comparative Study[Experimental prospective cognitive study on the evaluation of connection of fatigue perception and depression among caregivers and team treating cancer patients receiving oral chemotherapy to systemic chemotherapy. Equi-Car 10 study].
The Equi-Car 10 is an spontaneous, observational study. The objective was to assess the connection of fatigue perception and depression of caregivers, oncological team and oncological patients in oral chemotherapy to intravenous ⋯ The results showed that cancer patients and caregivers have high levels of fatigue and depression both related to the disease stage and to the mode of drug administration. It is necessary to provide cancer patients and caregivers with appropriate psychological support and preventive programs for secondary and relapse prevention.
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G Ital Med Lav Ergon · Apr 2012
Comparative Study[Job satisfaction, job burnout and their relationships with work'and patients' characteristics: a comparison between intensive care units (ICU) and not-intensive care units (not-ICU)].
Health worker's population is espoused to high level of stress, and several studies highlight differences between intensive care units (ICU) and non-intensive care unit (non-ICU). Particular features of the job in ICU concern responsibilities for critically patients, highly advanced technology and need for quick decision. ⋯ Current study highlighted several differences among ICU and non-ICU workers' referred to work environment and psychological reactions.