Rheumatology

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• Rheumatology · Sep 2006

  Identification of parotid salivary biomarkers in Sjogren's syndrome by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry and two-dimensional difference gel electrophoresis.

  To identify the most significant salivary biomarkers in Sjögren's syndrome (SS) using proteomic methods. ⋯ The salivary proteomic profile of SS is a mixture of increased inflammatory proteins and decreased acinar proteins when compared with non-SS. Future studies will test the ability of these biomarker levels, alone and in combination, to diagnose the salivary component of SS.

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