Rheumatology
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Randomized Controlled Trial Multicenter Study Comparative Study
Celecoxib compared with sustained-release paracetamol for osteoarthritis: a series of n-of-1 trials.
To assess the use of n-of-1 trials for short-term choice of drugs for osteoarthritis, with particular reference to comparing the efficacy of sustained-release [SR] paracetamol with celecoxib in individual patients. ⋯ N-of-1 trials may provide a rational and effective method to best choose drugs for individuals with osteoarthritis. SR paracetamol is more useful than celecoxib for most patients of whom management is uncertain.
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Randomized Controlled Trial Multicenter Study
Validation of a Dutch translation of the fibromyalgia impact questionnaire.
To validate a Dutch translation of the fibromyalgia impact questionnaire (FIQ). ⋯ The Dutch FIQ is a valid instrument for measuring health status in FM, showing sufficient reliability, construct validity and responsiveness.
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Multicenter Study
Effect of patient characteristics on reported outcomes after total knee replacement.
To evaluate the effect of pre-intervention factors in patient-reported outcomes at 6 months post-operatively following total knee replacement. ⋯ The main predictor of outcome at 6 months post-operatively in all eleven domains was the pre-intervention score of each domain. Presence of social support, absence of low back pain and higher baseline SF-36 mental health score were related to the improvement in the health-related quality of life post-operatively.
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To cross-culturally adapt the Shoulder Pain and Disability Index (SPADI) from English into German, and to test the reliability and validity of the German version. ⋯ The German SPADI is a practicable, reliable and valid instrument, and can be recommended for the self-assessment of shoulder pain and function.
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To investigate the discrepancy between physician's and parent's global assessments of disease status and the factors explaining discordance in patients with juvenile idiopathic arthritis (JIA). ⋯ Parents and physicians often perceive the health status of children with JIA differently, with parents providing most frequently lower rating.