Cardiovascular research
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Cardiovascular research · Apr 1996
Randomized Controlled Trial Comparative Study Clinical TrialUltrafiltration after cardiopulmonary bypass in children: effects on hemodynamics, cytokines and complement.
The purpose of the study was to evaluate the clinical and hemodynamic effect of intraoperative extracorporeal ultrafiltration (UF) and its potential in reducing the plasma concentration of circulating cytokines and complement activation products following open heart surgery in children. ⋯ In this study no clinical or hemodynamic effect was registered after UF. TNF and C3a were occasionally detected in the ultrafiltrate but we were unable to demonstrate reduction of these or any of the other markers tested in the group subjected to ultrafiltration.