Microbes and infection
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Microbes and infection · Mar 2012
ReviewA battle for iron: host sequestration and Staphylococcus aureus acquisition.
The use of iron as an enzymatic cofactor is pervasive in biological systems. Consequently most living organisms, including pathogenic bacteria, require iron to survive and replicate. To combat infection vertebrates have evolved sophisticated iron sequestration systems against which, pathogenic bacteria have concomitantly evolved equally elaborate iron acquisition mechanisms.