Clinical immunology : the official journal of the Clinical Immunology Society

The most recent articles from: Clin. Immunol. December 2016

Clin. Immunol. · Dec 2016

Cross-reactive multifunctional CD4+ T cell responses against Salmonella enterica serovars Typhi, Paratyphi A and Paratyphi B in humans following immunization with live oral typhoid vaccine Ty21a.

The live oral typhoid vaccine Ty21a elicits predominantly CD8+, as well as CD4+ T cells mediated immune responses. Clinical field studies showed that Ty21a is moderately effective against S. Typhi and S. ⋯ Typhi and S. Paratyphi B, but not to S. Paratyphi A.

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