Journal of the Egyptian National Cancer Institute
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J Egypt Natl Canc Inst · Jun 2008
Treatment results of adults and children with medulloblastoma NCI, Cairo University experience.
To evaluate treatment outcome and prognostic factors of adults and pediatric medulloblastoma patients treated by adjuvant postoperative craniospinal irradiation (CSI) and chemotherapy. ⋯ Survival rates of medulloblastoma pediatric patients were better than the adult ones. Neuro-axis relapse was the most common site of relapse for pediatric patients. Late relapses, lateral tumor location and shorter median follow up were noted in adult patients. Advanced tumor stage, metastases at presentation, limited tumor resection were powerful prognostic factors among the pediatric patients. In addition, high risk category was shown to be a prognostic factor for both pediatric and adult patients.
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J Egypt Natl Canc Inst · Jun 2008
Pedicled gastrocnemius flap: clinical application in limb sparing surgical resection of sarcoma around the knee region and popliteal fossa.
To highlight on the versatility of superiorly based pedicled gastrocnemius muscle flap in the limb-sparing surgery for bone or soft tissue sarcoma around the knee and popliteal fossa. ⋯ The unique vascularization of the gastrocnemius muscle (one pedicle to each head), the size of the muscle belly, the fact that it is situated in the dissection field and that its transfer does not affect the function of the spared limb too adversely, makes it particularly suitable for limb sparing procedures for sarcoma in the region of the knee and popliteal fossa. The medial head is the workhorse muscle flap for soft tissue coverage of knee endoprothesis and reconstruction of extensor mechanism. This decreases the rate of complications and improves the functional outcome. Reconstruction of the soft issue defect improves wound healing, protects exposed deep structures and subsequently prevents wound problems, delays adjuvant therapy and secondary amputation.
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J Egypt Natl Canc Inst · Jun 2008
Long term behavior of pedicled vascularized fibular grafts in reconstruction of middle and distal tibia after resection of malignant bone tumors.
The aim of this study was to evaluate the long term behavior of pedicled vascualrized fibula graft in reconstruction of middle and distal tibia defects following malignant tumor resection with particular emphasis on success in limb salvage and the specific late related complications. ⋯ Long term follow-up of pedicled vascularized fibula in reconstruction of bony defects of the middle or distal tibia after bone tumor resection showed that it is a useful tool in the limb salvage procedure. It is a short procedure, inexpensive, with low rate of late complications. It has a good outcome regarding the union, hypertrophy and the functional outcome.