Journal of the Egyptian National Cancer Institute
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J Egypt Natl Canc Inst · Jun 2008
Treatment results of adults and children with medulloblastoma NCI, Cairo University experience.
To evaluate treatment outcome and prognostic factors of adults and pediatric medulloblastoma patients treated by adjuvant postoperative craniospinal irradiation (CSI) and chemotherapy. ⋯ Survival rates of medulloblastoma pediatric patients were better than the adult ones. Neuro-axis relapse was the most common site of relapse for pediatric patients. Late relapses, lateral tumor location and shorter median follow up were noted in adult patients. Advanced tumor stage, metastases at presentation, limited tumor resection were powerful prognostic factors among the pediatric patients. In addition, high risk category was shown to be a prognostic factor for both pediatric and adult patients.
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J Egypt Natl Canc Inst · Jun 2008
Pedicled gastrocnemius flap: clinical application in limb sparing surgical resection of sarcoma around the knee region and popliteal fossa.
To highlight on the versatility of superiorly based pedicled gastrocnemius muscle flap in the limb-sparing surgery for bone or soft tissue sarcoma around the knee and popliteal fossa. ⋯ The unique vascularization of the gastrocnemius muscle (one pedicle to each head), the size of the muscle belly, the fact that it is situated in the dissection field and that its transfer does not affect the function of the spared limb too adversely, makes it particularly suitable for limb sparing procedures for sarcoma in the region of the knee and popliteal fossa. The medial head is the workhorse muscle flap for soft tissue coverage of knee endoprothesis and reconstruction of extensor mechanism. This decreases the rate of complications and improves the functional outcome. Reconstruction of the soft issue defect improves wound healing, protects exposed deep structures and subsequently prevents wound problems, delays adjuvant therapy and secondary amputation.
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J Egypt Natl Canc Inst · Jun 2008
Long term behavior of pedicled vascularized fibular grafts in reconstruction of middle and distal tibia after resection of malignant bone tumors.
The aim of this study was to evaluate the long term behavior of pedicled vascualrized fibula graft in reconstruction of middle and distal tibia defects following malignant tumor resection with particular emphasis on success in limb salvage and the specific late related complications. ⋯ Long term follow-up of pedicled vascularized fibula in reconstruction of bony defects of the middle or distal tibia after bone tumor resection showed that it is a useful tool in the limb salvage procedure. It is a short procedure, inexpensive, with low rate of late complications. It has a good outcome regarding the union, hypertrophy and the functional outcome.
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J Egypt Natl Canc Inst · Mar 2007
Professor Hassan K. Awwad; The Father of Radiation Oncology and Radiobiology in Egypt and the Arab World, His Good Deeds Last Forever and Inspire us for the Future.
Our most respected professor Hassan K. Awwad passed away on January 5th, 2007, at the age of 81. He was considered as the father of radiotherapy in Egypt. ⋯ This second edition is really a totally new book coping with the advancement of knowledge reached till the end of 2006. We are sure that this book with all other good deeds performed by Prof. Awwad, will keep his memory in Egypt as well as elsewhere in the whole world.
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J Egypt Natl Canc Inst · Dec 2006
Clinical TrialOncoplastic resection of retroareolar breast cancer: central quadrantectomy and reconstruction by local skin-glandular flap.
Patients with central breast neoplasms account for 5 to 20% of breast cancer cases and, for a long time, they have been denied Breast Conservation Surgery (BCS) and conventionally treated with mastectomy. The high incidence of Nipple-Areola-Complex (NAC) involvement usually associated with these tumors necessitates nipple and areolar resection together with an adequate safety margin around the tumor, which yields an unacceptable cosmetic result. With the help of Oncoplastic Surgical Techniques, BCS can be offered to these patients. In this study central quadrantectomy and breast reconstruction by an infero-laterally based pedicled flap were evaluated. ⋯ Oncoplastic techniques have succeeded in expanding the role of BCS to retro-areolar tumors. Central quadrantectomy with repair by a skin-glandular flap is a relatively simple procedure that yields very satisfactory cosmetic results with minimal complications and it may be considered as one of the noteworthy therapeutic options for patients with central breast tumors.