Evidence-based dentistry
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Evidence-based dentistry · Jan 2012
CommentEvidence lacking to determine whether preoperative analgesic use reduces post dental treatment pain for children.
The Cochrane Oral Health Group Trials Register, CENTRAL, Medline, Embase, LILACS and the ISI Web of Knowledge and relevant dental journals were searched with no restrictions. ⋯ From the available evidence we cannot determine whether or not preoperative analgesics are of benefit in paediatric dentistry for procedures under local anaesthetic. There is probably a benefit in prescribing preoperative analgesics prior to orthodontic separator placement.
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Evidence-based dentistry · Jan 2012
CommentWeak evidence that oral midazolam is an effective sedative agent for children undergoing dental treatment.
Medline, Embase, Cochrane Central Register of Controlled Trials, Dissertation Abstracts, SIGLE, the WorldWideWeb (Google) and the Community of Science Database were searched for relevant trials and references. Reference lists from relevant articles were scanned and the authors contacted to identify trials and obtain additional information. There were no language restrictions. Trials pre-1966 were not searched. ⋯ There is some weak evidence that oral midazolam is an effective sedative agent for children undergoing dental treatment. There is very weak evidence that nitrous oxide inhalation may also be effective. There is a need for further well designed and well reported clinical trials to evaluate other potential sedation agents. Further recommendations for future research are described and it is suggested that future trials evaluate experimental regimens in comparison with oral midazolam or inhaled nitrous oxide.