Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
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Multicenter Study
A multicentre cohort study of serum and peritoneal biomarkers to predict anastomotic leakage after rectal cancer resection.
Anastomotic leakage (AL) is one of the most feared complications after rectal resection. This study aimed to assess a combination of biomarkers for early detection of AL after rectal cancer resection. ⋯ The combination of serum CRP and peritoneal MMP9 may be useful for earlier prediction of AL after rectal cancer resection. In clinical practice, this combination of biomarkers should be interpreted in the clinical context as with any other diagnostic tool.