Transplant infectious disease : an official journal of the Transplantation Society
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Comparative Study
A comparative study of the use of selective digestive decontamination prophylaxis in living-donor liver transplant recipients.
Bacterial infections are major causes of early morbidity and mortality after liver transplantation. Selective digestive decontamination (SDD) can be used pre-operatively for living-donor liver transplant (LD-LT), but its role in this setting remains controversial. ⋯ In conclusion, the use of SDD prophylaxis in LD-LT was not beneficial and should be avoided, as it offers no advantage and could potentiate the emergence of multidrug-resistant organisms.
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Kidney transplant recipients are at risk for life-threatening infections, which may affect the long-term prognosis. ⋯ Sepsis was chiefly related to bacterial pneumonia or urinary tract infection. Pneumocystis jirovecii was the leading opportunistic agent, with a trend toward an increase over time. Infections often induced severe graft function impairment. Baseline creatinine and cyclosporine therapy independently predicted the outcome.