Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association
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J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. · Jul 1995
A prospective study of mother-to-infant HIV transmission in tribal women from India.
The transmission of human immunodeficiency virus type 1 from infected mothers to their babies was assessed by serologic, virologic, and clinical means. Of the 160 antibody-positive women enrolled at the beginning of the study, 13 had overt clinical symptoms (CDC stage III/IV). Termination of pregnancy was done, on request, in seven of these cases. ⋯ None of the seronegative children reverted to seropositive status despite the fact that they were breast-fed. The majority of the seropositive children (63%) became symptomatic and clinically ill during infancy. The overall mother-to-infant vertical transmission rate was 48%.