International journal of physiology, pathophysiology and pharmacology
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Int J Physiol Pathophysiol Pharmacol · Jan 2016
ReviewProton pump inhibitor-induced hypomagnesaemia and hypocalcaemia: case review.
Proton pump inhibitor (PPI)-induced hypomagnesaemia is a rare but serious adverse effect of a widely prescribed medication. It has become an increasingly recognised complication since 2006, with the U. S. ⋯ A 91 year old male presented with tetany from severe hypomagnesaemia and hypocalcaemia. This condition occurred in the context of 18 months of PPI use, and resolved following cessation of PPI therapy and the replenishment of magnesium and calcium stores. Monitoring of magnesium, calcium and potassium levels is crucial in patients prescribed PPIs long-term; especially the elderly patient.