Journal of wound care
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Journal of wound care · Feb 2019
Meta AnalysisThe role of collagenase ointment in acute burns: a systematic review and meta-analysis.
A systematic review and meta-analysis was performed to summarise the state of the literature in regard to the efficacy and uses of clostridial collagenase ointment (CCO) in the burn patient. ⋯ CCO may be a safe and effective debridement agent for burn wounds with respect to decreasing wound healing time and minimising pain without increasing the risk of infection. It should be used on a case-by-case basis due to its financial cost, which may be offset by its ability to manage burns non-operatively.