British journal of rheumatology
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Clinical Trial Controlled Clinical Trial
A double-blind study of the simple analgesic nefopam in rheumatoid arthritis.
The role of pure analgesics in the management of rheumatoid arthritis (RA) remains uncertain. In a double-blind cross-over study of 27 patients, nefopam was a more effective analgesic than placebo when given as a supplement to anti-inflammatory drugs. ⋯ Side-effects occurred in 9 (35%) on nefopam and none on placebo. The results suggest a valuable supplementary role for analgesics such as nefopam in the treatment of RA.