Neuro-oncology

The most recent articles from: Neuro-oncology June 2008

Neuro-oncology · Jun 2008

Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma.

The purpose of this study is to estimate the maximum-tolerated dose (MTD) and describe toxicities and preliminary clinical effects of tipifarnib, a farnesyltransferase (FTase) inhibitor, administered concurrently with radiation therapy in children with newly diagnosed intrinsic diffuse brainstem glioma (BSG). Children >or=3 and
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