European journal of heart failure
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Eur. J. Heart Fail. · Nov 2016
Randomized Controlled TrialMultimodality imaging-guided left ventricular lead placement in cardiac resynchronization therapy: a randomized controlled trial.
Left ventricular (LV) lead position at the latest mechanically activated non-scarred myocardial LV region confers improved response to cardiac resynchronization therapy (CRT). We conducted a double-blind, randomized controlled trial to evaluate the clinical benefit of multimodality imaging-guided LV lead placement in CRT. ⋯ Multimodality imaging-guided LV lead placement towards the CS branch closest to latest mechanically activated non-scarred myocardial LV segment reduces the proportion of clinical non-responders to CRT. Larger long-term multicentre studies are needed.