European journal of heart failure
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Eur. J. Heart Fail. · Jun 2017
Urinary levels of novel kidney biomarkers and risk of true worsening renal function and mortality in patients with acute heart failure.
Recent studies indicate the need to redefine worsening renal function (WRF) in acute heart failure (AHF), linking a rise in creatinine with clinical status to identify patients who develop 'true WRF'. We evaluated the usefulness of serial assessment of urinary levels of neutrophil gelatinase-associated lipocalin (uNGAL), kidney injury molecule-1 (uKIM-1), and cystatin C (uCysC) for prediction of 'true WRF'. ⋯ Elevated levels of uNGAL and uKIM-1 may predict development of 'true WRF' in AHF.