Deutsche medizinische Wochenschrift
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Dtsch. Med. Wochenschr. · Apr 2021
Case Reports[First Cases of Multisystem Inflammatory Syndrome following SARS-CoV-2 infection in Adults in Germany].
Multisystem Inflammatory Syndrome is a rare condition that affects multiple organs following SARS-CoV-2 infection. It was first observed in children, however few cases of adults with Multisystem Inflammatory Syndrome (MIS-A) were published in the US and the UK. We present two cases of Multisystem Inflammatory Syndrome in adults which occurred in Germany. ⋯ Multisystem Inflammatory Syndrome presents as a chameleon of symptoms. In the context of the ongoing SARS-CoV-2 pandemic, rising numbers of cases in adults can be expected. In patients with fever, increased inflammation parameters and lack of other explanations, Multisystem Inflammatory Syndrome must be considered. Due to the potential severity of clinical courses and possible cardiac involvement, a therapy with hydrocortisone, ASS and immunoglobulins should be considered early.
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Invasive fungal infections are gaining increasing importance in intensive care medicine. The aim of this article is to present an update on recent developments in the field of invasive fungal infection in critically ill patients. Particular emphasis is placed on the recently described invasive mold infections in patients with acute respiratory distress syndrome due to influenza or COVID-19. Detecting high-risk patients and the optimal diagnostic and therapeutic strategies play a decisive role to improve outcome.
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Dtsch. Med. Wochenschr. · Apr 2021
[Banks, archives or libraries? Models for the ethical foundation of biobanks].
At present, when it comes to research with biomedical data, research interests and data protection seem to be irreconcilable. Such differences are best mediated by an institution. The presuppositions of biobanking can be productively questioned with respect to public libraries. These represent a successful combination of knowledge and power, security and freedom.
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Dtsch. Med. Wochenschr. · Apr 2021
Case Reports[De novo thombotic microangiopathy (TMA) after incompatible AB0 renal transplantation].
We report a 57-year-old patient admitted to our hospital for planned AB0-incompatible living kidney transplantation. ⋯ It has to be discussed whether an early use of eculizumab in cases of suspected de novo TMA is a safe way to prevent graft dysfunction and thus to improve the poor prognosis for graft and recipient described in the literature.
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Thrombus formation due to atrial fibrillation is the most common cause of embolic stroke. Anticoagulation offers an effective prophylaxis. ⋯ The most commonly and best studied devices for this are the WATCHMAN™ and the AMPLATZER Amulet™ Occluders. In this How-To article, the aim is to offer a general overview of the indications, contraindications and complications as well as the implantation and postoperative management of patients receiving LAA closure by example of the WATCHMAN FLX™ Occluder.