Deutsche medizinische Wochenschrift
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Dtsch. Med. Wochenschr. · Mar 1985
Clinical Trial[Long-term therapy of cancer pain. A controlled study on buprenorphine].
Sublingual tablets of buprenorphine (Temgesic sublingual) were given in a controlled trial of 41 patients for 2804 patient-days. With a mean starting dose of 1.09 mg and a final dose of 1.53 mg buprenorphine daily there was a good pain-relieving effect. ⋯ The trial did not reveal any direct pointers as to tolerance or addictiveness after long-term intake of the drug. Because of its effectiveness and good duration of action, as well as the absence of negative long-term effects, the drug can be recommended in the long-term management of cancer pain.
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Dtsch. Med. Wochenschr. · Mar 1985
Case Reports[Dantrolene in the treatment of life-threatening psychiatric disease pictures. A contribution to the therapy of the malignant neuroleptic syndrome and acute febrile catatonia].
The malignant neuroleptic syndrome and acute febrile catatonia are life-threatening psychiatric disorders which frequently are treated in intensive care units outside psychiatric departments. Their manifestations are very similar to those of anaesthesia-specific malignant hyperthermia. ⋯ One such case is reported. In a 23-year-old man with signs of acute febrile catatonia parenteral dantrolene and electroconvulsive shocks succeeded in counteracting the symptoms of the abnormally raised muscle metabolism.
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Dtsch. Med. Wochenschr. · Jan 1985
Case Reports[Hyperbaric oxygenation treatment of the after-effects of carbon monoxide poisoning].
Following a symptom-free interval of 2 weeks after acute carbon monoxide poisoning a 38-year-old previously healthy man gradually developed impairment of drive and movement, disturbed memory, disorientation, mutism and abnormal gait. Finally, an apallic syndrome developed. After a total of 40 periods of hyperbaric oxygen administration the patient recovered completely and resumed his work. ⋯ The electropolysomnograph changed in parallel to the clinical picture. Computed tomography on admission to hospital demonstrated a zone of lower density in the region of the right globus pallidus. This finding was no longer demonstrable after the patient had fully recovered.