International journal of clinical pharmacology, therapy, and toxicology
-
Int J Clin Pharmacol Ther Toxicol · Sep 1984
Comparative Study Clinical TrialDezocine for postoperative wound pain.
We assessed the analgesic effectiveness of a single intramuscular injection of dezocine, 10 mg or 15 mg; morphine, 10 mg; or a placebo in 160 patients with moderate to severe postoperative pain. Dezocine, 10 mg, was as effective as and had approximately the same duration of action as morphine, 10 mg. ⋯ A small percentage of patients suffered nausea and became sedated; the drugs and placebo, however, did not differ statistically with respect to the side effects. Blood pressure, heart rate, and respiratory rate generally were slightly decreased by both drugs.