Zeitschrift für die gesamte innere Medizin und ihre Grenzgebiete
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The clinical use of cytostatics belongs to the most difficult forms of pharmacotherapy. On account of the slight therapeutic breadth of these substances, their use is nearly regularly loaded with partly severe toxic side effects. In a survey of literature and with the help of own instances the possible toxic side effects, their diagnostics. prevention and therapy, concerning the various organ systems, are described. Due to their high potential toxicity cytostatics should be administered only by physicians experienced in this therapy under exactest indication.