Pulmonary medicine
-
Comparative Study Clinical Trial
Sarcoidosis treatment with antifungal medication: a follow-up.
The aim of the study was to compare treatment of sarcoidosis with antifungal or corticosteroid medication. ⋯ In patients with sarcoidosis antifungal medication (n = 29), corticosteroids (n = 21) or a combination (n = 27) was given. Nine patients allotted to antifungal medication were later given corticosteroids because of the lack of regression of the disease. X-ray scores for the severity of granuloma infiltration were determined. Chitotriosidase and angiotensin converting enzyme were determined. The time in months till remission was observed as well as the number of recurrences.
-
Observational Study
A simple clinical measure of quadriceps muscle strength identifies responders to pulmonary rehabilitation.
The aim was to determine if baseline measures can predict response to pulmonary rehabilitation in terms of six-minute walk distance (6MWD) or quality of life. Participants with COPD who attended pulmonary rehabilitation between 2010 and 2012 were recruited. Baseline measures evaluated included physical activity, quadriceps strength, comorbidities, inflammatory markers, and self-efficacy. ⋯ Lower baseline CRQ was the only independent predictor of CRQ response. A participant with relatively lower baseline quadriceps strength was the strongest independent predictor of 6MWD response. Metabolic disease may predict 6MWD response, but predictors of CRQ response remain unclear.
-
Few reports have been published regarding surveillance data for pulmonary hypertension, a debilitating and often fatal condition. ⋯ Pulmonary hypertension mortality and hospitalization numbers and rates increased from 1999 to 2008.