Neurorehabilitation and neural repair
-
Neurorehabil Neural Repair · Mar 2009
Randomized Controlled TrialBotulinum toxin-a in children with congenital spastic hemiplegia does not improve upper extremity motor-related function over rehabilitation alone: a randomized controlled trial.
Rehabilitation of the upper extremity in children with hemiplegic cerebral palsy has not been compared to the same intensity of therapy combined with injected botulinum toxin (BTX). ⋯ Functional rehabilitation therapies for the upper extremity increase manual isometric flexor force at the wrist and ROM, but BTX injections cause weakness and do not lead to better outcomes than therapy alone.
-
Neurorehabil Neural Repair · Mar 2009
Motor network changes associated with successful motor skill relearning after acute ischemic stroke: a longitudinal functional magnetic resonance imaging study.
. Motor learning mechanisms may be operative in stroke recovery and possibly reinforced by rehabilitative training. ⋯ . Restoration of hand function is associated with highly lateralized MISI. Activity in bilateral somatosensory association area and contralesional SII may represent cortical plasticity involved in successful motor recovery. The changes in motor activity between acute and chronic phases seem to correspond to a motor learning process.
-
Neurorehabil Neural Repair · Mar 2009
Neurophysiological alterations during strategy-based verbal learning in traumatic brain injury.
Verbal learning and strategic processing deficits are common sequelae of traumatic brain injury (TBI); however, the neurophysiological mechanisms underlying such deficits remain poorly understood. ⋯ After TBI, the DLPFC appears to be decoupled from other active brain regions specifically when strategic control is required. We hypothesize that approaches designed to help re-couple DLPFC under such conditions may aid TBI cognitive rehabilitation.
-
Neurorehabil Neural Repair · Mar 2009
On the relative contribution of the paretic leg to the control of posture after stroke.
Reduced postural steadiness and asymmetry of weight bearing are characteristic for posture after stroke. ⋯ Patients with severe motor impairments of the paretic leg employ an effective compensatory strategy consisting of asymmetric weight bearing and lateralized control.