Neurorehabilitation and neural repair
-
Neurorehabil Neural Repair · May 2014
Randomized Controlled TrialRandomized trial of a robotic assistive device for the upper extremity during early inpatient stroke rehabilitation.
A recent Cochrane Review showed that early robotic training of the upper limb in stroke survivors can be more effective than other interventions when improving activities of daily living involving the arm function is the aim of therapy. ⋯ The robot therapy by NeReBot did not lead to better outcomes compared with conventional inpatient rehabilitation.
-
Neurorehabil Neural Repair · May 2014
Mirrored feedback in chronic stroke: recruitment and effective connectivity of ipsilesional sensorimotor networks.
Mirrored feedback has potential as a therapeutic intervention to restore hand function after stroke. However, the functional (effective) connectivity of neural networks involved in processing mirrored feedback after stroke is not known. ⋯ Mirrored feedback recruits ipsilesional brain areas relevant for control of the affected hand. These data provide a neurophysiological basis by which mirrored feedback may be beneficial as a therapy for restoring function after stroke.
-
Neurorehabil Neural Repair · May 2014
Rehabilitation improves behavioral recovery and lessens cell death without affecting iron, ferritin, transferrin, or inflammation after intracerebral hemorrhage in rats.
Rehabilitation aids recovery from stroke in animal models, including in intracerebral hemorrhage (ICH). Sometimes, rehabilitation lessens brain damage. ⋯ Rehabilitation is an effective behavioral and neuroprotective strategy for ICH. Neither effect appears to stem from influencing iron toxicity or inflammation. Thus, additional work must identify underlying mechanisms to help further therapeutic gains.