Zhurnal mikrobiologii, epidemiologii, i immunobiologii
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Contemporary aspects ofthe problem ofdiseases caused by single-celled yeast fungi Pneumocystisjirovecii are examined. Pneumocystic infection affects children and adults with various manifestations of immunodeficiency, is a HIV-associated infection. Contemporary epidemiologic characteristics of this infection are presented, data on etiology, pathogenesis and clinical presentation ofpneumocystosis are provided, problems of laboratory diagnostics are elucidated. Morphologic, immunobiologic and molecular-genetic methods of detection of Pneumocystis jirovecii causative agent are described.
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Zh. Mikrobiol. Epidemiol. Immunobiol. · Mar 2012
Review[Staphylococcus enterotoxins, their properties and role as pathogenicity factors].
Data on staphylococci species producing staphylococcus enterotoxins (SE) are presented in the review. Genetics of toxin formation, SE biosynthesis, factors influencing SE formation (pH, temperature, effect of inductors and repressors), physical-chemical properties of SE, influence of temperature on enterotoxin stability, enterotoxin structure, immunologic properties, super antigen properties, SE mechanism of action, role of SE in nosocomial infections, intestine dysbacteriosis, atopic dermatitis, enterotoxin toxicity, clinical manifestations are examined.
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Zh. Mikrobiol. Epidemiol. Immunobiol. · Jan 2012
[Monitoring of implementation of international programs of poliomyelitis eradication and measles and rubella elimination in the Republic of Belarus].
Monitoring of implementation of international programs of poliomyelitis eradication, and measles and rubella elimination in the Republic of Belarus based on results of molecular-epidemiologic studies of 2009 - 2010. ⋯ The data obtained give evidence to conformance of the poliomyelitis, measles, rubella, innate rubella syndrome control implemented in the Republic of Belarus to WHO recommendations; maintenance of status of country as free from poliomyelitis and achievement of main criteria of elimination of both measles and rubella by 2010.
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Zh. Mikrobiol. Epidemiol. Immunobiol. · Nov 2011
[Microbial "friend-foe" identification in human intestine microsymbiocenosis].
Development of methodical approach of evaluation of microbial "friend-foe" identification in human intestine microsymbiocenosis. ⋯ Indigenous microflora during microsymbiocenosis formation can participate in "friend-foe" identification, the basis of which is determined by microsymbiont exometabolites. The data obtained open a perspective of understanding mechanisms of intramicrobial interactions and can be used for both diagnostics and optimal selection of "candidates" during creation of new probiotics and synbiotics.
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Zh. Mikrobiol. Epidemiol. Immunobiol. · Jul 2011
Clinical Trial[Vaccination against influenza A (H1N1) in pregnancy].
Evaluation of alterations of immune response regulation and possible risk of antenatal development of fetus in postvaccination period in pregnant women immunized against influenza A (H1N1). ⋯ Vaccination of pregnant women against influenza A (H1N1) by Russian subunit formulation (MonoGrippol plus) showed reactogenicity comparable to control group by the level of influence on general metabolic and immunologic homeostasis and on the course of pregnancy, which is an evidence of its safety.