Journal of the American Medical Directors Association
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Comparative Study
Depression, frailty, and all-cause mortality: a cohort study of men older than 75 years.
Depression is associated with increased mortality, but it is unclear if this relationship is truly causal. ⋯ Current, but not past, depression is associated with increased mortality, and this excess mortality is strongly associated with frailty. Interventions designed to decrease depression-related mortality in later life may need to focus on ameliorating frailty in addition to treating depression.
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The aim of this study was to evaluate the relationship between chronic kidney disease (CKD) and cognitive decline in community-dwelling older adults without dementia. ⋯ A lower level of kidney function was associated with lower cognitive performance in attention and processing speed. These results suggest that eGFR might be an effective method to screen for cognitive decline in community-dwelling older adults.