Pain medicine : the official journal of the American Academy of Pain Medicine
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Arthritis of the knee affects 46 million Americans. We aimed to determine the level of evidence of intraarticular knee injections in the management of arthritic knee pain. ⋯ We conclude that strong evidence supports the use of intraarticular knee injection as a valuable intervention in the continuum of management of arthritis between conservative treatment and knee surgeries.
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This article is aimed at critically evaluating the evidence from systematic reviews (SRs) of spinal manipulation in patients with pain. ⋯ Collectively, these data fail to demonstrate that spinal manipulation is an effective intervention for pain management.
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Multicenter Study
Pain in postsurgical orthopedic rehabilitation: a multicenter study.
The aim of this study was to quantify and characterize pain in patients undergoing lower limb postsurgical orthopedic rehabilitation and to investigate the impact of pain in slowing or interrupting their rehabilitation. ⋯ In light of the high occurrence and intensity of pain in the sample, and of the significant impact on the rehabilitation program, clinicians should pay more attention to pain, especially neuropathic pain, in postsurgical patients. Tailored pain pharmacological therapy could possibly improve patient compliance during the rehabilitation process and enhance long-term outcomes.
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Randomized Controlled Trial
Randomized, double-blind, placebo-controlled study of the abuse potential of different formulations of oral oxycodone.
The objective of this study was to evaluate the pharmacokinetics and abuse potential of different formulations of oxycodone. ⋯ Intact, orally administered oxycodone CR produced less drug liking and high than IR oxycodone, and required approximately twofold greater doses to produce subjective effects comparable to IR oxycodone.
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The objective of this study was to quantify the network complexity, information flow, and effect of critical-node failures on a prototypical regional anesthesia and perioperative pain medicine (RAPPM) service using social network analysis. ⋯ The RAPPM service entails considerable network complexity and increased hierarchy, but low centrality. The network is at considerable fragmentation risk from even single-node failure.