Infusionstherapie und klinische Ernährung
-
Infusionsther Klin Ernahr · Apr 1987
Randomized Controlled Trial Comparative Study Clinical Trial[Comparative study of the modification of blood, blood coagulation, cardiovascular circulation by 3% modified, fluid gelatins and 6% low-molecular weight hydroxyethyl starch].
A randomized, comparative study with 3% modified fluid gelatine and 6% low molecular hydroxyethylstarch has been made on 87 patients of an intensive care unit. Both plasma substitutes were well compatible to the patients. The erythrocyte sedimentation rate was accelerated significantly by both plasma substitutes. ⋯ The gelatine substitute showed a significant rise in blood pressure after end of infusion, the hydroxyethylstarch substitute did not. Both substitutes showed a rise in diuresis with a delay of 1 h. There were no differences between both solutions in the diuretic effect after infusion.
-
Infusionsther Klin Ernahr · Jun 1986
Randomized Controlled Trial Clinical Trial[Volume replacement with a new hydroxyethyl starch preparation (3 percent HES 200/0.5) in heart surgery].
In a randomized study including 55 patients undergoing elective aorto-coronary bypass surgery efficacy of a low concentrated hydroxyethylstarch (3% HES 200/0.5) was tested after extracorporeal circulation (ECC). All patients received 1,000 ml autologous washed erythrocytes (cell saver) and 400 ml fresh frozen plasma (FFP). ⋯ With regard to hemodynamic efficiency and the change in laboratory data no relevant differences between group I, II and III could be seen. EVLW-measurement demonstrated the lowest increase in lung water after infusion of HES; simultaneously pulmonary gas exchange was less compromised in comparison to the other infusion groups. 3% HES 200/0.5 solution can be considered as an effective volume substitute with short intravascular retention time, which seems to be of advantage in patients coming off extracorporeal circulation.
-
Infusionsther Klin Ernahr · Jun 1981
Randomized Controlled Trial Clinical Trial[Effect of hydroxyethyl starch HES 450/0.7 and 5% human albumin on the colloid osmotic pressure and hemodynamic parameters in hypovolemic patients after major abdominal procedures].
In a randomized study 20 patients with hypovolemia following abdominal surgery for malignoma were treated with 500 ml HES 450/0.7 or human albumin 5% during the first 24 h after operation. COP and various blood- and hemodynamic parameters were measured immediately before and after infusion as well as 2, 4 and 6 h after infusion. After HES-infusion COP increased from 20.2 to about 22 mmHg and remained at a significantly higher level (p less than 0.01) for 6 h. ⋯ In the albumin-group CVP increased from the same starting level only to 4.2 cmH2O, and then dropped back to 3.2 cmH2O after 6 h (no significant difference to the starting level). The other blood- and hemodynamic parameters measured showed no significant differences between the two groups. The results show that a quick and reliable improvement of hypovolemia can be obtained in both groups immediately after infusion, but that the COP- and volume-stabilizing effects of HES-infusion are more distinct and remained for a significantly longer period of time than the effects of albumin 5%-infusion.