São Paulo medical journal = Revista paulista de medicina
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Prevention of recurrence of stroke depends on recognition of the underlying mechanism of ischemia. ⋯ Detecting the presence of PAF by screening patients with no AF in the ECG through Holter ECG examinations is valuable in terms of changing the course of the treatment. It should be kept in mind that the possibility of accompanying PAF cannot be ruled out in the presence of other factors that pose a risk of stroke.
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Gastrointestinal (GI) symptoms are frequent complaints from individuals with nonalcoholic fatty liver disease (NAFLD). Dyspepsia is a universal clinical symptom and is among the most common GI complaints observed in the general population, but its prevalence in the population with NAFLD has not been previously investigated. ⋯ FD occurs more frequently in individuals with NAFLD than in controls without hepatic disease.
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In this era of target therapies, novel data on the correlation between response endpoints and survival outcomes in multiple myeloma have arisen. ⋯ This analysis demonstrated that the quality of response after application of first-line treatment using novel agent-based regimens among multiple myeloma patients was a prognostic factor for PFS and OS, which are the most clinically relevant outcomes.
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Anxiety and depression are the most prevalent mental disorders worldwide. However, the exact mechanisms linking chronic obstructive pulmonary disease (COPD) with depression and anxiety have not been identified. ⋯ This study showed that there were higher levels of depression and anxiety among COPD patients than among healthy controls.
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Because normal male sexual differentiation is more complex than normal female sexual differentiation, there are more cases of disorders of sex development (DSDs) with 46,XY karyotype that have unclear etiology. However, Leydig and Sertoli cell markers are rarely used in distinguishing such individuals. ⋯ According to our findings, we can speculate that inhibin B levels may be used to differentiate among DSD cases.