[Hokkaido igaku zasshi] The Hokkaido journal of medical science
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Hokkaido Igaku Zasshi · Sep 1997
[Experimental studies concerning about the effects of the portal arterialization 4 weeks after ligation of hepatic artery under the optimal arterio-portal shunt blood flow].
The changes of hepatic hemodynamics and hepatic oxygen metabolism after portal arterialization (APS) were studied. Beagle dogs were used for the experiments. Dogs were grouped as follows: group I (n = 6) had 2 days of APS, group II (n = 6) had 1 week of APS, group III (n = 6) had 4 weeks of APS. ⋯ AKBR and mGOT were not significantly different compared with the preoperative level in all groups. Histologically, the liver structure, common bile duct and portal vein showed no ischemic change compared with the control biopsy in all groups. In conclusion, this study showed portal arterialization under the optimal arterio-portal shunt flow has beneficial effects on liver under hepatic arterial obstruction for 4 weeks.