The journal of pain : official journal of the American Pain Society
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Chronic pain is associated with many negative consequences for individuals and society. Given the burden it represents, many studies have focused on the risk factors involved, but very few have aimed to explain why some people live well with chronic pain, beyond the psychological realm. Thus, this study collected and analyzed different individual experiences to identify the pivotal conditions that help some individuals achieve quality of life despite chronic pain, with an emphasis on social considerations. ⋯ The data collected suggest that to enable people to have a favorable evolution in the presence of chronic pain, a socio-ecological approach could be necessary to counteract painogenic environments. However, these results need to be validated and adapted to different populations. Perspective This study highlights the importance of a socio-ecological approach to living well with chronic pain, emphasizing that care partnerships, a nurturing environment and the ability to break with the past are essential to improve the quality of life of those affected.
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Review
Exploring the emotional impact of pain on children and adolescents: a poetic meta-ethnography.
EXPLORING THE EMOTIONAL IMPACT OF PAIN ON CHILDREN AND ADOLESCENTS: A META-ETHNOGRAPHIC POETIC SYNTHESIS: Pain in early life can go unreported and untreated. We use poems to portray findings from a systematic review of qualitative research. The overall aim of the review was to distil essential experiences across pain conditions and contexts. ⋯ PERSPECTIVE: The voices of young people in pain are not always heard. This article presents themes, in poetic form, from a synthesis of 189 qualitative studies. Science and art are integral to leaps in understanding and inclusive arts-based research methods have the potential to underpin compassionate pain care for young people.
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Studies have revealed a comorbidity to be common between patients with migraine and those with psychiatric disorders, such as bipolar disorder (BD) and major depressive disorder (MDD). However, considering the substantial epidemiological differences in the prevalence of migraine between Western and Asian countries, further investigation was required to determine whether findings regarding familial coaggregation of migraine and psychiatric disorders can be generalized to Asian populations. Using the Taiwan National Health Insurance Database, we included 822,773 first-degree relatives (FDRs) of individuals with migraine and 3,291,092 FDRs of individuals without migraine. ⋯ Thus, clinicians should closely monitor the mental health of FDRs of individuals with migraine. PERSPECTIVE: First-degree relatives of migraine probands had an increased risk of being diagnosed with psychiatric disorders, including schizophrenia, bipolar disorder, major depressive disorder, anxiety disorders, and alcohol or substance use disorders. They also died by suicide, regardless of the individual migraine and psychiatric comorbidities.
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Chronic pain impacts 11-33% of children and will continue into adulthood for over half of them. Transition of pain management to adult care is crucial given high risk of interruption of care which is associated with subsequent poor medical, social, and vocational outcomes. Yet the transition experience for these youth is poorly characterized. ⋯ PERSPECTIVE: This article establishes low readiness to transition from pediatric to adult healthcare among adolescents with chronic pain and identifies disparities in readiness. Poor mental health and inadequate healthcare access were identified as factors which may impact transition intervention delivery. These findings can guide development and implementation of a transition intervention.
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Autoimmunity and immunoglobulin G (IgG) autoantibodies may contribute to pain in a subset of fibromyalgia (FM) patients. Previously, IgG from FM patients was found to induce pain-like behavior in mice and bind to satellite glial cells (anti-SGC IgG). The anti-SGC IgG levels were also associated with more severe symptomatology. ⋯ Additionally, FM severe had higher LPC 19:0, 22:0, and 24:1 and lower sphingomyelin (n = 9) concentrations compared to FM mild. Positive associations were seen for LPC 22:0 and 24:1 with pain intensity and anti-SGC IgG levels in FM subjects. Taken together, these results suggest an association between altered lipid metabolism and autoimmune mechanisms in FM.