Clinical breast cancer
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Clinical breast cancer · Jun 2017
Validating the IBIS and BOADICEA Models for Predicting Breast Cancer Risk in the Iranian Population.
Several approaches have been suggested for incorporating risk factors to predict the future risk of breast cancer. The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) and International Breast Cancer Intervention Study (IBIS) are among these approaches. We compared the performance of these models in discriminating between cases and noncases in the Iranian population. ⋯ The IBIS model discriminated cases and noncases better than the BOADICEA model in the Iranian population. However, the discrimination of the logistic regression model, which included a larger array of familial, genetic, and personal risk factors, was better than the 2 models.
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Clinical breast cancer · Jun 2017
Oncologic Safety of Immediate Breast Reconstruction in Breast Cancer Patients Who Underwent Neoadjuvant Chemotherapy: Short-Term Outcomes of a Matched Case-Control Study.
Although the indication for immediate breast reconstruction (IBR) after skin-sparing mastectomy (SSM) or nipple-sparing mastectomy (NSM) has been expanded, IBR after neoadjuvant chemotherapy (NACT) is still controversial. We conducted retrospective matched case-control study to analyze oncologic outcomes between patients who underwent TM only and those who underwent IBR after SSM or NSM after NACT. ⋯ IBR after SSM or NSM might be a feasible surgical treatment option even in breast cancer patients who underwent NACT.