Sleep medicine
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Multicenter Study Comparative Study
Benefit and risk of modafinil in idiopathic hypersomnia vs. narcolepsy with cataplexy.
The benefit/risk ratio of modafinil was recently re-evaluated by the European Medicines Agency and was shown to be negative for idiopathic hypersomnia (IH) because of insufficient data. ⋯ Modafinil has an excellent benefit/risk ratio in idiopathic hypersomnia, with or without long sleep time, similar to its effect on narcolepsy/cataplexy.