American journal of physiology. Endocrinology and metabolism
The most recent articles from:
September 2008
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Am. J. Physiol. Endocrinol. Metab. · Sep 2008
ReviewWhy are we shaped differently, and why does it matter?
Body fat distribution is an important predictor of metabolic abnormalities in obese humans. Dysregulation of free fatty acid (FFA) release, especially from upper body subcutaneous adipose tissue, appears to contribute substantially to these metabolic disturbances. ⋯ Regional variations in the storage of fatty acids, both meal derived and direct reuptake, and storage of circulating FFAs that may help to explain why some depots expand at the expense of others have been reported. We review the quantitative data on regional lipolysis, meal, and FFA storage in adults to provide an overview of fat balance differences in adults with different fat distribution patterns.