Roczniki Państwowego Zakładu Higieny
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Rocz Panstw Zakl Hig · Jan 1997
[Evaluation of the combined effect of lead and sodium nitrite on some blood biochemical parameters in blood of rats during subchronic exposure. Influence on levels of methemoglobin, sulfhydryl groups and tryptophan].
The study was performed on 4 groups of male Wistar rats, receiving p.o. through 3 months every day: 1) distilled. water (control group); 2) sodium nitrite in dose 30 mg/kg b.w. x day (20% LD50); 3) lead acetate in dose 10 mg/kg b.w. x day (6.7% LD50); 4) lead acetate and sodium nitrite in amounts as above. The methemoglobin and hemoglobin were determined in whole blood, tryptophan--in plasma and free sulfhydryl groups--in erythrocytes. ⋯ Both nitrite and lead significantly decrease free sulfhydryl groups and tryptophan levels in blood. There was also observed that lead administrated together with sodium nitrite does not increase methemoglobin concentration.
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The purpose of the study was to assess the effects of various pipelines on drinking water quality. For the study carried out in Warsaw buildings were chosen in which the installations were made of polypropylene, polyvinyl chloride, copper and steel. Water samples were taken from the sites of water leading to the buildings and from the highest floors, if possible. ⋯ The hydro-biological testing of water samples included quantitative and qualitative analysis of macroscopic and microscopic plant and animal organisms. All studies were carried out according to Polish Standards and the methods of the State Institute of Hygiene. The results of the physicochemical, bacteriological and hydro-biological tests failed to show any effect of the material of pipelines on the quality of drinking water in the range of the determined parameters.