Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
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1. Donor assessment scores can be used to prognosticate recipient outcomes but are often not clinically relevant. 2. The donor risk index, the survival outcomes following liver transplantation score, and the Donor Model for End-Stage Liver Disease score have specific advantages and disadvantages with respect to accuracy and ease of use. 3. The significance of the donor assessment is undermined by an allocation system that sometimes limits ideal donor-recipient matching and whose sole objective is the minimization of wait-list mortality instead of the benefit of transplantation.
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1. Comprehend the basis for liver allocation and distribution in the United States. 2. Understand potential solutions to organ inequalities in the United States. 3. Understand the metrics used to assess the performance of organ procurement organizations.
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The objective of this study was to identify peritransplant predictors of early graft survival and posttransplant parameters that could be used to predict early graft outcomes after pediatric liver transplantation (PLT). The response of children to liver dysfunction after liver transplantation (LT) is poor. No data have been reported for early predictors of poor graft survival, which would potentially be valuable for rescuing children at risk after LT. ⋯ The NNT with early retransplantation when the day 7 bilirubin level was >200 μmol/L was 2.17 (unadjusted) or 2.76 (adjusted for graft survival). In conclusion, 2 scores-the product of the peak AST level, day 2 INR value, and day 7 bilirubin level and a posttransplant day 7 bilirubin level > 200 μmol/L-have been identified as clinically valuable tools with high accuracy for predicting early graft loss. A more aggressive attitude to considering early retransplantation in this group may further improve survival after LT.