Drug and therapeutics bulletin
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At any one time, most 16-18-years-old and up to half of adults have acne. In 60% of all teenagers, the condition will be sufficiently severe for them to self-treat or seek medical advice. ⋯ However, there have been suggestions that the drug itself might cause depression and suicide. Here we consider these concerns, and the implications for the use of isotretinoin when managing patients of all ages.