European annals of otorhinolaryngology, head and neck diseases
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Eur Ann Otorhinolaryngol Head Neck Dis · Nov 2019
Randomized Controlled TrialEffect of single-dose intravenous tranexamic acid on postoperative nasal bleed in septoplasty.
Postoperative nasal bleeding is a common complication of septoplasty and may lead to painful procedure of nasal packing to stop bleeding. Since Tranexamic acid (TXA) has been reported to reduce bleeding, the purpose of this study is to investigate the effect of single dose of intravenous TXA on postoperative nasal bleed associated with septoplasty. ⋯ Single intravenous dose of TXA is shown to be effective and safe agent in preventing postoperative nasal bleeding after septoplasty therefore avoiding additional techniques of nasal packing, intranasal splint or trans-septal suturing during surgery.