BJOG : an international journal of obstetrics and gynaecology
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Randomized Controlled Trial Multicenter Study Clinical Trial
The effect of a novel vaginal ring delivering oestradiol acetate on climacteric symptoms in postmenopausal women.
Evaluate the efficacy and acceptability of a novel vaginal ring delivering oestradiol acetate (Menoring) versus oral oestradiol for relief of climacteric symptoms in postmenopausal women. ⋯ The oestradiol vaginal ring significantly improved climacteric symptoms as measured by Greene Climacteric Scale scores and reduced the frequency of hot flushes/night sweats. Efficacy and safety of vaginal ring oestradiol were comparable with those of oral therapy. Patient evaluations of oestradiol vaginal ring tolerability and acceptability were excellent.