BJOG : an international journal of obstetrics and gynaecology
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To determine the therapeutic efficacy and safety of a nitric oxide (NO) isosorbide dinitrate donor to induce cervical ripening of women with missed abortions before surgical evacuation of the uterus. ⋯ Intracervical administration of 80 mg isosorbide dinitrate in women with missed abortions appears to be effective for cervical ripening prior to surgical evacuation of the uterus. Differences in the incidence of non-serious adverse events are not likely to be clinically significant.
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Randomized Controlled Trial
A randomised controlled trial to evaluate the effect of self-administered analgesia on women's experience of outpatient treatment at colposcopy.
To evaluate the effect of self-administered isoflurane and desflurane on women's experience of outpatient treatment at colposcopy. ⋯ Satisfaction with outpatient treatment at colposcopy is generally high. The main effect of isoflurane and desflurane evaluated in this trial was to reduce pain. It appeared to be effective for women with clinically significant anxiety and could be offered as an alternative to general anaesthesia.
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The United Kingdom Amniotic Fluid Embolism Register was established to identify the incidence of the condition and examine any differences or common factors between survivors and fatalities. ⋯ The mortality of amniotic fluid embolism is high but the majority of women will survive. There is significant maternal and neonatal morbidity even when the woman survives. Continuing assessment of cases of amniotic fluid embolism is important to identify ways of improving outcome.