BJOG : an international journal of obstetrics and gynaecology
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Multicenter Study Comparative Study
Advanced maternal age and pregnancy outcomes: a multicountry assessment.
To assess the association between advanced maternal age (AMA) and adverse pregnancy outcomes. ⋯ Advanced maternal age predisposes women to adverse pregnancy outcomes. The findings of this study would facilitate antenatal counselling and management of women in this age category.
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Multicenter Study
Development of criteria for identifying neonatal near-miss cases: analysis of two WHO multicountry cross-sectional studies.
To develop and test markers of neonatal severe morbidity for the identification of neonatal near-miss cases. ⋯ Newborn infants presenting selected markers of severity and surviving the first neonatal week could be considered as neonatal near-miss cases. This definition and criteria may be seen as a basis for future applications of the near-miss concept in neonatal health. These tools can be used to inform policy makers on how best to apply scarce resources for improving the quality of care and reducing neonatal mortality.
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Multicenter Study
Education and severe maternal outcomes in developing countries: a multicountry cross-sectional survey.
To assess the relationship between education and severe maternal outcomes among women delivering in healthcare facilities. ⋯ Women with lower levels of education are at greater risk for severe maternal outcomes, even after adjustment for key confounding factors. This is particularly true for women in countries that have poorer markers of social and economic development.
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Multicenter Study
Indirect causes of severe adverse maternal outcomes: a secondary analysis of the WHO Multicountry Survey on Maternal and Newborn Health.
To assess the proportion of severe maternal outcomes resulting from indirect causes, and to determine pregnancy outcomes of women with indirect causes. ⋯ Indirect causes were responsible for about one-fifth of severe maternal outcomes. Women with underlying indirect causes had significantly increased risks of severe maternal and perinatal outcomes.
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To undertake a cost-effectiveness analysis that compares positron emission tomography - computed tomography (PET-CT) imaging plus standard practice with standard practice alone in the diagnosis of recurrent or persistent cervical cancer during routine surveillance and follow-up of women who have previously been diagnosed and treated. ⋯ The results of the current analysis suggest that use of PET-CT in the diagnosis of recurrent or persistent cervical cancer is not cost-effective. Current guidelines recommending imaging using PET-CT as a diagnostic or surveillance tool need to be reconsidered in light of these results. This study did not specifically investigate the use of PET-CT in women with symptoms and radiological suspicion of recurrence where exenteration was considered. More research in that specific area is required.