BJOG : an international journal of obstetrics and gynaecology
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To determine whether outpatient exposure to calcium-channel blockers (CCBs) at the time of delivery is associated with an increased risk for postpartum haemorrhage (PPH). ⋯ The outpatient use of CCBs in late pregnancy for the treatment of hypertension does not increase the risk of PPH.
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Multicenter Study Comparative Study
Maternal and neonatal morbidity in relation to the instrument used for mid-cavity rotational operative vaginal delivery: a prospective cohort study.
To compare the maternal and neonatal morbidity associated with alternative instruments used to perform a mid-cavity rotational delivery. ⋯ Maternal and perinatal outcomes are comparable with Kielland forceps, vacuum extraction, and manual rotation, with few serious adverse outcomes. With appropriate training mid-cavity rotational delivery can be practiced safely, including the use of Kielland forceps.
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Multicenter Study Observational Study
Birth defects in a national cohort of pregnant women with HIV infection in Italy, 2001-2011.
We used data from a national study of pregnant women with HIV to evaluate the prevalence of congenital abnormalities in newborns from women with HIV infection. ⋯ This study adds further support to the assumption that first-trimester exposure to antiretroviral treatment does not increase the risk of congenital abnormalities.
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To describe the trends of severe perineal tears in England and to investigate to what extent the changes in related risk factors could explain the observed trends. ⋯ Changes in major risk factors are unlikely explanations for the observed increase in the rate of third- or fourth-degree tears. The improved recognition of tears following the implementation of a standardised classification of perineal tears is the most likely explanation.
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To assess the risk of further surgery amongst women who had an initial endometrial ablation (EA) for the treatment of heavy menstrual bleeding (HMB). ⋯ One in six women have further surgery after EA for HMB, which is a higher rate than reported in clinical trials. This risk of further surgery decreases with age.