BJOG : an international journal of obstetrics and gynaecology
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Review Meta Analysis
Timing of administration of prophylactic antibiotics for caesarean section: a systematic review and meta-analysis.
Prophylactic antibiotics reduce infectious morbidity from caesarean section. The timing of their administration, however, is a matter of controversy. ⋯ Compared with intraoperative administration, preoperative antibiotics significantly reduce the rate of endometritis. The lack of neonatal adverse effects should be cautiously interpreted given the limited power of the trials to detect such effects.
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Economic evaluations of health interventions pose a particular challenge for reporting. There is also a need to consolidate and update existing guidelines and promote their use in a user friendly manner. The Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement is an attempt to consolidate and update previous health economic evaluation guidelines efforts into one current, useful reporting guidance. ⋯ To facilitate dissemination and uptake, the CHEERS statement is being co-published across 10 health economics and medical journals. We encourage other journals and groups, to endorse CHEERS. The author team plans to review the checklist for an update in 5 years.
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Review Meta Analysis Comparative Study
Effect of misoprostol versus oxytocin during caesarean section: a systematic review and meta-analysis.
The efficacy of misoprostol versus oxytocin for reducing blood loss during caesarean section remains unclear. ⋯ The results suggest that misoprostol is as effective as oxytocin for reducing blood loss during caesarean section. However, further research into treatment strategies is needed.