Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova
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Fiziol Zh SSSR Im I M Sechenova · Jul 1989
Comparative Study[Insulin and glucocorticoid binding by blood cell receptors after hydrocortisone administration in rabbits].
Repeated i.v. administration of hydrocortisone (10 mg/kg) revealed an increase in the resistance against insulin although endogenous corticosterone was decreased in 33 male rabbits. The insulin- and dexamethasone-binding receptors of erythrocytes and mononuclear leucocytes. changed after 3-7 hydrocortisone injections, the binding increasing for insulin and diminishing for dexamethasone.