Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova
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Fiziol Zh SSSR Im I M Sechenova · Aug 1989
Comparative Study[The interrelations of arterial pressure, cardiac output and coronary blood flow during orthostatic reactions].
The influence of hypotension induced with orthostasis, upon cardiac output and coronary flow was studied in anesthetized cats. The body tilt to 15-60 degrees lowered the mean arterial pressure parallel with reduction of cardiac output. Under the tilt up to 30 degrees and 60 degrees, a significant difference was found in decrease of systolic but not diastolic pressures. ⋯ The findings suggest a participation of vascular constrictor responses in the forming of orthostatic reactions. The coronary flow decrease only began with the tilt up to 30 degrees. Its extent did not depend on the intensity of hypotension being, probably, the result of the reduction of the heart work.